The prevalence of infertility worldwide is estimated to be between 10% and 15% in the general population. Infertility can develop due to various causes, including genetic factors such as Y chromosome microdeletions, congenital absence of the vas deferens associated with cystic fibrosis, Klinefelter syndrome, and Turner syndrome.
Infertility may be inherited within families. In some cases, the genetic disorders causing infertility may occur in an individual without affecting any other family members.
For the diagnosis of infertility, it is essential for family members to be evaluated by both a gynecologist and a urologist. Families diagnosed with infertility should consult a genetics center for a comprehensive genetic evaluation before starting treatment processes, alongside other assessment results. This approach can be beneficial for determining the underlying cause of infertility and for supporting the family's chances of having a healthy child.