Genetic Factors in Infertility
Globally, infertility affects approximately 10%–15% of the population. While it can result from various causes, some cases are linked to genetic factors, including:
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Y chromosome microdeletions
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Congenital absence of the vas deferens associated with cystic fibrosis
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Klinefelter syndrome
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Turner syndrome
Infertility can also be inherited within families, although in some cases, the genetic condition causing infertility may not have been previously observed in other family members.
Why Genetic Evaluation Is Important
Diagnosis of infertility requires thorough evaluation by both a gynecologist and a urologist.
Once a diagnosis is made, before initiating treatment, couples should consult a genetic center for a full genetic assessment. This process helps:
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Identify the underlying cause of infertility
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Guide treatment decisions
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Support the couple’s chances of having a healthy child
Genetic analysis before treatment begins is a critical step in reproductive care.