Gluten causes damage to the intestines in individuals with gluten sensitivity and leads to the formation of antibodies against certain tissues. Symptoms may include abdominal pain, itchy and recurring non-healing sores, bloating, diarrhea, constipation, fatigue, and skin rashes. Due to gluten consumption, diseases such as celiac disease, dermatitis herpetiformis, gluten-sensitive ataxia, and non-celiac gluten sensitivity can occur. The most well-known of these diseases, celiac disease, is a chronic, autoimmune disease. It is a disease that occurs in genetically predisposed individuals, triggered by gluten intake, and affects the small intestine.
Especially individuals who have family members with gluten-related diseases may be genetically predisposed to this condition. Therefore, it is important for individuals who exhibit signs of gluten-related diseases to undergo genetic evaluation. The results of genetic tests can help determine a person’s risk of gluten sensitivity, assist in the early diagnosis of the disease, and help manage treatment more effectively. Abnormal antibody test and intestinal biopsy results are not mandatory.
It is important for individuals who show signs of gluten-related diseases to undergo genetic testing and adjust their diet accordingly. While genetic tests can help determine the risk of disease, dietary and lifestyle changes can help manage symptoms and prevent disease progression.
